Clinical Evidence
Hyperbaric oxygen therapy (HBOT) delivers 100% oxygen at elevated atmospheric pressure, increasing dissolved oxygen in plasma and driving oxygen into hypoxic tissues.
A substantial and growing body of peer-reviewed clinical evidence demonstrates HBOT’s therapeutic value across five domains directly relevant to Special Operations Forces readiness:
This brief compiles the strongest available clinical studies across these domains, drawn from randomized controlled trials, meta-analyses, systematic reviews, and prospective cohort studies. Each study title links directly to its PubMed record or publisher page for verification. The evidence base is particularly robust for cognitive recovery following mild traumatic brain injury, a finding directly aligned with the Secretary of Defense’s current emphasis on cognitive performance across the force.